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Ovation Abstract on Artificial Intelligence in IVF Nominated for Awards at ESHRE in Vienna

An Ovation® Fertility abstract about the use of artificial intelligence in IVF, presented at the 35th European Society of Human Reproduction and Embryology (ESHRE) Annual Meeting on June 24, 2019, was pre-selected for consideration for two prestigious awards at the event.

An Ovation® Fertility abstract about the use of artificial intelligence in IVF, presented at the 35th European Society of Human Reproduction and Embryology (ESHRE) Annual Meeting on June 24, 2019, was pre-selected for consideration for two prestigious awards at the event: The Basic Science Award for Oral Presentation, awarded to the presenting author of the best oral presentation on a basic science topic, and the Fertility Society of Australia Exchange Award, which provides an educational travel grant for the presenting author to present the data of his/her oral presentation at the annual meeting of the Fertility Society of Australia (FSA).

Only five presentations at ESHRE 2019 were selected to receive awards and be rewarded with a prize of EURO 2,000, and one additional presentation was selected for the FSA Exchange Award. Special award committees, composed of senior scientists and clinicians, made the selections for each award.

Ovation’s oral presentation about the use of artificial intelligence in IVF, “Artificial intelligence (AI) technology can predict human embryo viability across multiple laboratories with varying demographics with high accuracy and reproducibility,” detailed a study that sought to find out if artificial intelligence (AI) and computer vision can improve embryo viability prediction using static 2D images of Day 5 embryos from multiple laboratories.

In most IVF labs, embryologists select which embryos to transfer based on morphological assessment, using high-powered microscopes to examine each embryo and assign it a subjective “grade.” Invasive embryo biopsy is also used to evaluate embryo potential through genetic testing. For this international study, 7,847 microscope images of embryos from 12 IVF laboratories in four countries were used to train and develop the Life Whisperer embryo viability assessment model, which employs a combination of computer vision and deep-learning artificial intelligence to evaluate the viability of Day 5 human blastocysts using static 2D images.

The study found that the AI model was 32% more accurate in assessing embryo viability than traditional embryologist morphology assessment. For the first time, these data represent how an AI model can be applied across a multicenter, mixed demographic dataset, resulting in approximately 70% overall accuracy for viable and non-viable embryo identification.

“It is a tremendous honor to be pre-selected for award consideration at ESHRE, as fewer than 1% of submissions are selected for award consideration in the opening-session oral presentations,” says presenting author and Ovation Fertility laboratory director Matthew “Tex” VerMilyea, PhD. “Our study proves that AI can remove the subjectivity of human morphological grading and provide a robust and consistent platform for standardizing embryo selection. This improved predictive accuracy should result in improved pregnancy success rates and reduce the time to achieve a successful pregnancy, and the accuracy will only increase over time as more data are collected through use of AI.”

The international collaborative study’s authors include:

  1. Corresponding/Presenting Author: Matthew D. VerMilyea (Ovation Fertility, Austin/San Antonio, TX, USA)
  2. Andrew Miller (Ovation Fertility, Austin, TX, USA)
  3. Michelle Lane (Repromed, Adelaide, Australia; Monash IVF Group, Richmond, Australia)
  4. Glen Adaniya (Ovation Fertility, Indianapolis, ID, USA)
  5. Bradford Bopp (Midwest Fertility Specialists, Carmel, ID, USA)
  6. Dean E. Morbeck (Fertility Associates, Auckland, New Zealand)
  7. Erica Behnke (Ovation Fertility, Cincinnati, OH, USA)
  8. Leah Click (Institute of Reproductive Health, Cincinnati, USA)
  9. Rebecca Matthews (Oregon Reproductive Medicine, Portland, USA)
  10. Adelle Lim (Alpha Fertility Centre, Petaling Jaya, Malaysia)
  11. Jonathan Hall (Life Whisperer, Adelaide, Australia)
  12. Michelle Perugini (Life Whisperer, Adelaide, Australia)
  13. Don Perugini (Life Whisperer, Adelaide, Australia)
  14. Andrew Murphy (Life Whisperer, Adelaide, Australia)

In addition to the award-nominated oral presentation, three other Ovation abstracts were chosen for poster presentations at ESHRE 2019, giving Ovation an overall acceptance rate of 100% at the event for the second consecutive year.

About Ovation Fertility

Ovation® Fertility is a national network of reproductive endocrinologists and scientific thought leaders focused on reducing the cost of having a family through more efficient and effective fertility care. Ovation’s IVF and genetics laboratories and affiliated practices work collaboratively to raise the bar for IVF treatment, with state-of-the-art, evidence-based fertility services that give hopeful parents the best chance for a successful pregnancy. Physicians partner with Ovation to offer their patients advanced preimplantation genetic testing. Ovation also provides donor eggs that come with the world’s first Euploid Embryo Guarantee®, as well as secure frozen egg, embryo and sperm long-term storage; consultative services to help IVF laboratories improve quality and performance; and fertility preservation programs that enable more women to freeze their eggs and build future families. Learn more about Ovation’s vision of a world without infertility at www.OvationFertility.com.

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