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The Effect Of ICM Positioning Inside Or Outside Of The Zona Pelucida On Pregnancy Rates Of PGT-A Euploid Single Embryo Transfers

Title: The Effect Of ICM Positioning Inside Or Outside Of The Zona Pelucida On Pregnancy Rates Of PGT-A Euploid Single Embryo Transfers

Authors: Davis, A.1, Bopp, B.2, Will, M.2, Anspach Will, E.2, O’Leary, K.2, Adaniya, G.1

Objective: Embryos fully enclosed in the zona pellucida (ZP) may survive freeze and warm processes better than fully hatched embryos. The objective of this study is to discover if the position of the inner cell mass (ICM) inside or outside the ZP affects the embryo potential on pregnancy rates after freezing and warming when the embryo is not fully hatched. This comparison will find if the ICM outside of the ZP leads to a difference in embryo potential.

Presented at: 65th AAB Conference 25th CRB Symposium & Cryopreservation Workshop May 9-12, 2023 Las Vegas, Nevada

Why This Research Helps Patients:
Embryologists are constantly searching for ways to optimize embryo selection to ensure the patient's best chances of success with each euploid single embryo transfer. Learning what morphological characteristics impact the embryo's possible potential can help embryologists choose the embryo that has the maximum potential for pregnancy.

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