Genetic Testing You Can Trust
Ovation® Genetics’ national network of genetics laboratories helps people have successful pregnancies by providing genetic testing for conditions that could lead to infertility, pregnancy loss or genetic illnesses in children.
Using the most advanced technology available, Ovation provides both carrier screening and preimplantation genetic testing (PGT) to fertility centers across the United States and around the world, backed by an unprecedented level of patient and customer support. Ovation continues to raise the bar for the science of IVF, in partnership with our collaborative of IVF laboratories and affiliated practices that includes many of the brightest minds and leaders in reproductive medicine.
Preconception Carrier Screening
The American Congress of Obstetricians and Gynecologists (ACOG) and the American College of Medical Genetics (ACMG) recommends that everyone planning a pregnancy have preconception carrier screening. This type of genetic testing can help determine whether a you or your partner are carriers and are at risk of passing on a preventable genetic condition.
Ovation Carrier Screening analyzes your DNA to determine whether you carry any of 300+ genetic abnormalities that can lead to serious genetic conditions in your children. This valuable screening helps identify conditions such as cystic fibrosis, fragile X syndrome, sickle cell anemia and Tay-Sachs, among many others.
You and your fertility specialist will receive a detailed, easy-to-read report that outlines your results, and you’ll also be eligible to receive a one-on-one consult with a board certified genetic counselor to help you better understand your risk and plan your next steps.
Preimplantation Genetic Testing
Ovation Genetics’ national network of genetics laboratories also provides three types of preimplantation genetic testing (PGT) of embryos created through IVF. If you are found to have an increased risk of having a child with a genetic condition, your fertility specialist may recommend IVF with one or more types of preimplantation genetic testing to identify which of your embryos to transfer to reduce your risk and give you the highest likelihood of having a healthy baby.
PGT-A: Preimplantation genetic testing for aneuploidy. PGT-A analyzes the 23 pairs of chromosomes within individual cells from each embryo. Embryos with a normal number of chromosomes are called “euploid” and are most likely to result in a successful pregnancy. Those with ab-normal chromosome composition are called aneuploid, and are most likely to either not implant or result in a baby with a genetic condition, such as Down syndrome.
PGT-M: Preimplantation genetic testing for monogenic/single-gene defects. Rather than counting chromosomes in cells taken from embryos, as with PGT-A, PGT-M examines specific genes, searching for a specific genetic defect that is known to run in your family or for which you or your partner is known to be a carrier.
PGT-SR: Preimplantation genetic testing for chromosomal structural rearrangements. Performed in conjunction with PGT-A, PGT-SR tests your embryos for specific structural rearrangements for which you and/or your partner are at risk. Such rearrangements can increase the chance of implantation failure, miscarriage or the birth of a baby with a chromosome disorder.
By selecting embryos to transfer that have been genetically tested, you can significantly increase the chances of a healthy pregnancy and baby. PGT, which you may see referred to as preimplantation genetic screening (PGS) or preimplantation genetic diagnosis (PGD), has been proven to improve pregnancy rates and reduce the chance of miscarriage, and it can also unlock the mystery of unexplained infertility, recurrent miscarriages and failed IVF cycles.
PGT gives your physician a valuable tool to increase the chances of success with an elective single embryo transfer (eSET), which may give you A Quicker Path to PregnancyTM. Transferring one euploid embryo reduces the risk of multiples and helps reduce the emotional, financial and health risks of transferring untested embryos that may appear “normal” from a subjective visual interpretation.
PGT can be valuable for all hopeful parents using IVF to conceive and is especially useful and highly recommended for certain groups of patients, such as those with:
- Advanced maternal age (35 years or older)
- Previous IVF failure
- A previous child with a genetic condition
- A history of recurrent miscarriages
- Unexplained infertility
- Family history of genetic disease
To learn more about our genetics laboratories and how Ovation Genetics can help you plan your future family, please contact us for more information.